SML3134
Tabernanthalog fumarate
≥98% (HPLC)
Synonym(s):
1,2,3,4,5,6-Hexahydro-8-methoxy-3-methyl-azepino[4,5-b]indole fumarate, 8-Methoxy-3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole fumarate, TBG fumarate
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About This Item
Empirical Formula (Hill Notation):
C14H18N2O · C4H4O4
CAS Number:
Molecular Weight:
346.38
UNSPSC Code:
12352200
SMILES string
O=C(O)/C=C/C(O)=O.CN1CCC(NC2=C3C=CC(OC)=C2)=C3CC1
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Tabernanthalog (TBG) is a water-soluble, non-hallucinogenic and non-toxic ibogaine analog with potent 5-HT2A receptor (human and mouse) agonist and 5-HT2B receptor (human) antagonist activities, but no opioid agonist activity.TBG induces rat dendritic growth blockable by the 5-HT2A antagonist ketanserin in cultures and exhibits antidepressant-like efficacy in vivo (50 mg/kg via i.p. by mouse forced swimming or alcohol consumption, 40 mg/kg by rat heroin self-administration).
Water-soluble, non-hallucinogenic, non-toxic ibogaine analog with 5-HT2A agonist and 5-HT2B antagonist potency, and in vivo antidepressant-like efficacy.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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