SML3637
YM-254890
≥95% (HPLC), Gαq/11 protein inhibitor, Powder or Lyophilized powder or film
Synonym(s):
N-Acetyl-L-threonyl-(aR)-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-2-(acetylamino)-3-hydroxy-4-methyl-1-oxopentyl]oxy]-L-leucyl-N,O-dimethyl-L-threonine (7→1)-lactone, QS 3666A, YM 254890
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About This Item
Empirical Formula (Hill Notation):
C46H69N7O15
CAS Number:
Molecular Weight:
960.08
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
(Powder or Lyophilized powder or film)
Product Name
YM-254890, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
form
(Powder or Lyophilized powder or film)
color
white to off-white
storage temp.
-10 to -25°C
Biochem/physiol Actions
Gaq/11 protein inhibitor
YM-254890, a cyclic depsipeptide isolated from the culture broth of Chromobacterium sp., is a cell-permeable, potent and selective inhibitor of Gαq/11 protein. YM-254890 specifically inhibits the GDP/GTP exchange by blocking GDP release from the Gq protein.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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