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Merck
CN

SML3649

Sigma-Aldrich

Ozenoxacin

≥98% (HPLC)

Synonym(s):

1-Cyclopropyl-8-methyl-7-(5-methyl-6-methylamino-pyridin-3-yl)-4-oxo1,4-dihydro-quinoline-3-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C21H21N3O3
CAS Number:
Molecular Weight:
363.41
MDL number:
UNSPSC Code:
51111800
NACRES:
NA.25
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Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

SMILES string

[n]2(c3c([c](c(c2)C(=O)O)=O)ccc(c3C)c4cnc(c(c4)C)NC)C1CC1

InChI

1S/C21H21N3O3/c1-11-8-13(9-23-20(11)22-3)15-6-7-16-18(12(15)2)24(14-4-5-14)10-17(19(16)25)21(26)27/h6-10,14H,4-5H2,1-3H3,(H,22,23)(H,26,27)

InChI key

XPIJWUTXQAGSLK-UHFFFAOYSA-N

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Biochem/physiol Actions

Ozenoxacin is a quinolone antimicrobial that inhibits bacterial DNA replication enzymes, DNA gyrase A and topoisomerase IV
Quinolone antimicrobial that inhibits bacterial DNA replication enzymes, DNA gyrase A and topoisomerase IV

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Y López et al.
Antimicrobial agents and chemotherapy, 57(12), 6389-6392 (2013-10-02)
In vitro activity of ozenoxacin, a novel nonfluorinated topical (L. D. Saravolatz and J. Leggett, Clin. Infect. Dis. 37:1210-1215, 2003) quinolone, was compared with the activities of other quinolones against well-characterized quinolone-susceptible and quinolone-resistant Gram-positive bacteria. Ozenoxacin was 3-fold to

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