SML3787
Pexiganan acetate
≥98% (HPLC)
Synonym(s):
GIGKFLKKAKKFGKAFVKILKK-NH2 acetate, Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-lIe-Lys-Lys-NH2 acetate, MSI 78 acetate, MSI-78 acetate, MSI78 acetate
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About This Item
Empirical Formula (Hill Notation):
C122H210N32O22 · xC2H2O4
CAS Number:
Molecular Weight:
2477.17 (free base basis)
NACRES:
NA.21
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
(Powder or Lyophilized powder or film)
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
(Powder or Lyophilized powder or film)
storage condition
desiccated
color
white to off-white
storage temp.
-10 to -25°C
Biochem/physiol Actions
Cationic antimicrobial peptide (AMP) with broad-spectrum activity against Gram-positive and Gram-negative bacteria.
Pexiganan (MSI-78) is a 22-aa synthetic cationic antimicrobial peptide (AMP), an analog of magainin found in the African clawed frog (Xenopus laevis). Pexiganan is effective against both Gram-positive (staphylococci MIC ≤16 µg/mL, streptococci & methicillin-resistant S. aureus MIC 8-64 µg/mL, S. pyrogenes MIC 16-256 µg/mL) and Gram-negative aerobes (MIC 4-32 µg/mL, E. cloacae MCI 1-128 µg/mL, A. faecalis 4-64 µg/mL) by disrupting bacteria cell wall or membrane.
Disclaimer
Hygroscopic
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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