SML3801
Trospium chloride
≥98% (HPLC)
Synonym(s):
(1α,3β,5α)-3-[(hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium] chloride, Azoniaspiro(3α-benziloyloxynortropane-8,1′-pyrrolidine) chloride
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About This Item
Empirical Formula (Hill Notation):
C25H30NO3·Cl
CAS Number:
Molecular Weight:
427.96
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Product Name
Trospium chloride, ≥98% (HPLC)
InChI key
RVCSYOQWLPPAOA-QKYUOBHYNA-M
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Peripheral muscarinic receptor antagonist
Trospium chloride is a peripheral muscarinic receptor antagonist that relaxes the smooth muscle in the bladder. It does ot cause central nervous system side effects typical for other drugs of its class. Trospium chloride is used for the treatment of overactive bladder.
Disclaimer
Hygroscopic
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial
The Journal of Urology, 171(6 Pt 1), 2311-2315 (2004)
Cognitive Effects of Anticholinergic Load in Women with Overactive Bladder
Clinical Interventions in Aging, 15, 1493-1503 (2020)
Kelly Biastre et al.
The Annals of pharmacotherapy, 43(2), 283-295 (2009-02-06)
To review the pharmacology, pharmacokinetics, safety, and clinical application of trospium chloride for the management of overactive bladder (OAB). Clinical literature including both primary sources and review articles was accessed through MEDLINE, International Pharmaceutical Abstracts, and Cochrane databases from 1980
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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