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Merck
CN

SML3866

SCR2682

≥98% (HPLC)

Synonym(s):

N-[4-(2-Bromo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide

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About This Item

Empirical Formula (Hill Notation):
C21H27BrN2OS
CAS Number:
Molecular Weight:
435.42
NACRES:
NA.21
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

room temp

Biochem/physiol Actions

Potent and selective opener of neuronal Kv7/KCNQ/M-channels that activates the native M-current in rat hippocampal or cortical neurons
SCR2682 is potent and selective opener of neuronal Kv7/KCNQ/M-channels that activates the native M-current in rat hippocampal or cortical neurons. It reverses epileptic seizures in rodents. SCR2682 relieves mechanical allodynia and thermal hyperalgesia in rat models of pain.


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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