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Merck
CN

SML3930

SDM25N

≥98% (HPLC)

Synonym(s):

(4bS,8R,8aS,14bR)-5,6,7,8,14,14b-Hexahydro-7-(2-methyl-2-propenyl)-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, N-2-Methylallyl-noroxymorphindole, SDM 25N, SDM-25N, TU 753, TU-753, TU753

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About This Item

Empirical Formula (Hill Notation):
C26H26N2O3
CAS Number:
Molecular Weight:
414.50
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Potent and highly selective delta-opioid receptor (DOR) antagonist.

SDM25N (TU753) is a potent and highly selective delta-opioid receptor (DOR) antagonist (δ/κ/μ Ki = 4.7 nM/3.8 μM/7.9 μM). SDM25N is also reported to inhibit Dengue virus (DENV) that restricts genomic RNA replication (EC50 = 1.9 μM using Hela DENV2 replicon cells) by targeting the viral NS4B protein.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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