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Merck
CN

SML3940

KNX-002

≥98% (HPLC)

别名:

N-[1-(4-Methoxyphenyl)cyclopropyl]-3-(2-thienyl)-1H-pyrazole-4-methanamine

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关于此项目

经验公式(希尔记法):
C18H19N3OS
化学文摘社编号:
分子量:
325.43
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

COC1=CC=C(C2(CC2)NCC3=CNN=C3C4=CC=CS4)C=C1

InChI

1S/C18H19N3OS/c1-22-15-6-4-14(5-7-15)18(8-9-18)19-11-13-12-20-21-17(13)16-3-2-10-23-16/h2-7,10,12,19H,8-9,11H2,1H3,(H,20,21)

InChI key

CXRMCTBDMZVPNE-UHFFFAOYSA-N

Biochem/physiol Actions

Cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA).



KNX-002 is a cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA) that has no or little effect on the vertebrate myosins tested. KNX-002 obstructs efficient ATP hydrolysis thus inhibiting motor activity. KNX-002 inhibits parasite motility and growth.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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