SML4020
XQ2B
≥95% (HPLC)
Synonym(s):
Cyclo(D-Phe-Ala-Thr-Arg-Leu-D-Phe-Pro-Val-Arg-Leu)
Quality Level
Assay
≥95% (HPLC)
form
(Powder or Lyophilized powder or film)
color
white to off-white
storage temp.
-10 to -25°C
SMILES string
O=C([C@H]1N(C([C@H](NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N2)[C@H](C)O)=O)=O)=O)CC3=CC=CC=C3)=O)CCC1)N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](CC4=CC=CC=C4)C(N[C@H](C2=O)C)=O)=O)=O)CCCNC(N)=N)=O)C(C)C
Biochem/physiol Actions
XQ2B, macrocyclic peptide derived from Gramicidin S, acts a specific cyclic GMP-AMP synthase (cGAS) inhibitor by directly targeting protein-DNA interface. XQ2B attenuates the host innate antiviral response.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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