SML4067
MCLA Hydrochloride
≥98% (HPLC)
Synonym(s):
2-Methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one HCl, 3,7-Dihydro-2-methyl-6-(4-methoxyphenyl)imidazol[1,2-a]pyrazine-3-one HCl, 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one HCl, 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride, MCLA HCl
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About This Item
Quality Level
Assay
≥98% (HPLC)
form
powder
color
, Faint yellow to very dark orange
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
SMILES string
O=C1C(C)=NC2=CNC(C3=CC=C(OC)C=C3)=CN21.Cl
Biochem/physiol Actions
MCLA (methoxylated Cypridina luciferin analog) is a highly sensitive probe employed in the detection of reactive oxygen species (ROS), particularly superoxide anion (O2•−) and singlet oxygen (1O2). It is notable for its blue luminescence (~ 455 nm), which is a critical indicator in ROS detection. MCLA′s detection mechanism involves oxidation to a probe radical, which then reacts with O2•− to produce luminescence. MCLA offers a broad dynamic range, making it versatile for both intracellular measurements in live cells and extracellular detection in various sample types. Its application is particularly significant in research related to oxidative stress, inflammation, and neurodegenerative diseases, where ROS play a pivotal role. Ex: ~ 430 nm, Em: ~ 549 nm.
Disclaimer
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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