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Merck
CN

SML4121

Erythrodiol

≥98% (HPLC)

Synonym(s):

3β-Erythrodiol, Oleanolic alcohol, (3β)-Olean-12-ene-3,28-diol, Olean-12-ene-3β,28-diol, (+)-Erythrodiol, 3β,28-Dihydroxyolean-12-ene

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About This Item

Empirical Formula (Hill Notation):
C30H50O2
CAS Number:
Molecular Weight:
442.72
MDL number:
NACRES:
NA.21
UNSPSC Code:
41116107
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

SMILES string

C[C@@]12C([C@@]3([H])[C@@](CC2)(CCC(C)(C3)C)CO)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O)C)C

Biochem/physiol Actions

Natural pentacyclic triterpenoid that exhibits anti-inflammatory, antioxidant, and antitumor properties, and enhances cholesterol efflux.

Erythrodiol, also known as Oleanolic alcohol, is a natural triterpene found in olive oil and other plants, known for its multi-faceted pharmacological actions. It displays anti-inflammatory effects by inhibiting pro-inflammatory cytokines and modulating enzymes involved in inflammation. As an antioxidant, it scavenges free radicals, mitigating oxidative stress. In addition, erythrodiol exhibits antitumor properties through antiproliferative activities like inducing cancer cell apoptosis and cell cycle arrest. Erythrodiol also enhances cholesterol efflux in macrophages by increasing the half-life of the ATP-binding cassette transporter A1 (ABCA1) protein, primarily by preventing its degradation.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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