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Merck
CN

SML4161

Enrofloxacin hydrochloride

new

≥98% (HPLC), powder, Fluoroquinolone antibiotic

Synonym(s):

1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride, Enrofloxacin HCl

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About This Item

Empirical Formula (Hill Notation):
C19H22FN3O3.HCl
CAS Number:
93106-59-3
Molecular Weight:
395.86
MDL number:
MFCD01861684

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

SMILES string

OC(C1=CN(C2CC2)C3=CC(N4CCN(CC)CC4)=C(F)C=C3C1=O)=O.Cl

General description

Enrofloxacin hydrochloride is a fluoroquinolone antibiotic withbroad-spectrum activity, which kills bacteria by blocking DNA gyrase and typeIV topoisomerase interaction with DNA. This antibiotic belongs to the fluoroquinolone group,specifically the 6-fluoro-7-piperazinyl-4-quinolones. Enrofloxacinhydrochloride is effective against both Gram-negative and Gram-positivebacteria. It is commonly used in veterinary medicine. Enrofloxacin HClexhibits better water solubility than enrofloxacin.

Application

Enrofloxacin hydrochloride may be used in studies assessing the presence of enrofloxacin in water sources, contributing to environmental safety and pollution control. It may also be used in analytical methods for detecting enrofloxacin residues in food products, ensuring compliance with safety regulations.

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Sicong Qiao et al.
Journal of medicinal chemistry, 68(14), 14312-14332 (2025-05-09)
Aging induces dysfunction and increases the risk of chronic diseases in the elderly, positioning the development of antiaging drugs to the forefront of research. Drug repurposing offers an efficient strategy for identifying antiaging lead compounds. In this study, we employed
Enrofloxacin?The Ruthless Killer of Eukaryotic Cells or the Last Hope in the Fight against Bacterial Infections?
Grabowski L, et al.
International Journal of Molecular Sciences, 23 (2022)

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