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About This Item
Empirical Formula (Hill Notation):
C18H20FN3O4 · xHCl
CAS Number:
Molecular Weight:
361.37 (free base basis)
MDL number:
NACRES:
NA.21
UNSPSC Code:
41116107
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C1C2=CC(F)=C(C3=C2N([C@H](CO3)C)C=C1C(O)=O)N4CCN(C)CC4.[xHCl]
General description
Levofloxacin is the L-isomer of the racemic fluoroquinolone, ofloxacin. It has a more intricate fused ring structure that is linked to the oxazinoquinoline core as compared to quinolones. Levofloxacin is a broad-spectrum fluoroquinolone antibiotic that exhibits high water solubility. While the hydrochloride form of levofloxacin is freely soluble in water, levofloxacin itself is only sparingly soluble in aqueous solutions.
Application
Levofloxacin hydrochloride may be used to:
- investigate its antibacterial effects against Gram-positive and Gram-negative bacteria
- assess environmental antibiotic pollution
- study drug–food interactions in pharmacokinetic research by evaluating the impact of dietary interventions on quinolone bioavailability
Biochem/physiol Actions
Levofloxacin is a fluoroquinolone antibiotic with broad-spectrum activity, the optical S-(-) isomer of ofloxacin, which kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.
Disclaimer
Hygroscopic Store with desiccant
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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