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About This Item
Empirical Formula (Hill Notation):
C18H20FN3O4 · xHCl
CAS Number:
Molecular Weight:
361.37 (free base basis)
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C(O)C1=CN2C3=C(OCC2C)C(N4CCN(C)CC4)=C(F)C=C3C1=O.[xHCl]
General description
Ofloxacinhydrochloride is a broad-spectrum fluoroquinolone antibiotic that exhibitswater solubility, whereas ofloxacin itself is only sparingly soluble in aqueoussolutions.
Application
Ofloxacin hydrochloride may be used as a standard to study theadsorption behaviour of antibiotics.
Biochem/physiol Actions
Ofloxacin kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. Ofloxacin has 100 times higher affinity for bacterial DNA gyrase than for mammalian. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.
Disclaimer
Hygroscopic Store with desiccant
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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