Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
General description
Eribulin is a synthetic analog of Halichondrin B, a compound isolated from the sea sponge Halichondria okadai.
Application
Eribulin may be used for investigating its effects on tumor microenvironment and tumor vasculature.
Biochem/physiol Actions
Eribulin is a microtubule dynamics inhibitor that results in prolonged mitotic arrest and subsequent apoptosis. It suppresses microtubule dynamic instability at plus ends through an inhibition of microtubule growth with little or no effect on shortening. Eribulin displays anticancer activity by inhibiting the proliferation of multiple cancer cell types.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Muta. 2 - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable