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About This Item
Empirical Formula (Hill Notation):
C19H18BF2N4· BF4
Molecular Weight:
437.99
UNSPSC Code:
12352200
Assay:
≥90% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated, protect from light
Quality Level
assay
≥90% (HPLC)
form
powder
storage condition
desiccated, protect from light
color
orange to very dark brown
solubility
DMSO: 2 mg/mL, clear
shipped in
wet ice
storage temp.
-10 to -25°C
Biochem/physiol Actions
m-Diazonium BODIPY is a fluorogenic probe engineered for site-specific labeling of tyrosine residues in amino acids, peptides, proteins, and intricate biomolecules via an azo-coupling reaction, facilitating the formation of fluorescent biosensors. The design of BODIPY m-diazonium ensures precise targeting and uniform labeling under physiological conditions, achieving high conversion rates during the coupling process without inducing epimerization of the asymmetric carbon in L-Tyr-OH. Tyrosine-specific BODIPY labeling of FKBP12 enables selective fluorescence detection of tacrolimus (KD = 45 nM) with a sensitivity threshold of 190 nM. The excitation and emission wavelengths are approximately 495 nm and 525 nm, respectively.
Disclaimer
Hygroscopic, store with desiccant
flash_point_c
Not applicable
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML4367-5MG | 04065273872255 |
| SML4367-25MG | 04065273872248 |