SRP0426
PDE1B active rat
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
Synonym(s):
PDE1B1, PDES1B, phosphodiesterase 1B, calmodulin-dependent
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
rat
recombinant
expressed in baculovirus infected Sf9 cells
Assay
≥70% (SDS-PAGE)
form
aqueous solution
mol wt
89 kDa
packaging
pkg of 10 μg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... PDE1B(5153)
General description
Rat PDE1B (GenBank Accession No. NM_022710) full length with N-terminal HIS-GST-tag, MW= 89kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Andrew T Bender et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(2), 497-502 (2004-12-31)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a major regulator of monocyte to macrophage differentiation. In both humans and mice, the main phenotype of decreased GM-CSF function is pulmonary proteinosis due to aberrant function of alveolar macrophages. Recently, this cytokine has been
Andrew T Bender et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(2), 460-465 (2006-01-13)
Monocyte-to-macrophage differentiation with the cytokine granulocyte-macrophage colony-stimulating factor induces expression of the cyclic nucleotide phosphodiesterase PDE1B2. However, what role PDE1B2 plays in macrophage biology has not been elucidated. We have addressed this question by inhibiting PDE1B2 induction by using RNA
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