SRP0486
Bromodomain Non-Acetylated Ligand 1
≥95% (HPLC)
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Product Name
Bromodomain Non-Acetylated Ligand 1, ≥95% (HPLC)
assay
≥95% (HPLC)
form
aqueous solution
mol wt
2602.1 kDa
packaging
pkg of 5 mL
shipped in
dry ice
storage temp.
−20°C
General description
The Bromodomain Non-acetylated Ligand 1 is peptide histone H4 (1-21). It contains an C-terminal GG linker, followed by a biotinylated Lys. Bromodomains function as acetyl-lysine binding domains, and bromodomain/acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. This peptide is suitable for use as a ligand for several bromodomains including members of the BET bromodomain family: BRD2, BRD3, BRD4, and BRDT. It contains an C-terminal GG linker, followed by a biotinylated Lys. Bromodomains function as acetyl-lysine binding domains, and bromodomain/acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. This peptide is suitable for use as a negative control for several bromodomains including ATAD2 and BAZ2B.
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Pil-Hoon Park et al.
American journal of physiology. Gastrointestinal and liver physiology, 289(6), G1124-G1136 (2005-08-06)
Ethanol treatment increases gene expression in the liver through mechanisms that are not clearly understood. Histone acetylation has been shown to induce transcriptional activation. We have investigated the characteristics and mechanisms of ethanol-induced histone H3 acetylation in rat hepatocytes. Immunocytochemical
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