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Merck
CN

SRP2144

SRC1, receptor interaction domain (627-786), GST tagged human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

Synonym(s):

F-SRC-1, KAT13A, MGC129719, MGC129720, RIP160, SRC1, bHLHe42, bHLHe74

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About This Item

NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Concentration:
500 μg/mL
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biological source

human

recombinant

expressed in E. coli

assay

≥80% (SDS-PAGE)

form

frozen liquid

mol wt

~44 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

500 μg/mL

color

clear colorless

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... NCOA1(8648)

Biochem/physiol Actions

Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptors and has been previously used in assays detecting ligand-dependent receptor-cofactor interactions.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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