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Merck
CN

SRP4207

JE (MCP-1) from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym(s):

CCL2, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Small inducible cytokine A2

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
MFCD00131621

Key Documents

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Product Name

JE (MCP-1) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

biological source

mouse

recombinant

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

potency

1-20 ng/mL ED50

mol wt

~13.8 kDa

packaging

pkg of 10 μg

impurities

endotoxin, tested

NCBI accession no.

P10148

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ccl2(20296)

General description

mouse JE (also known as Macrophage/Monocyte Chemotactic Protein) is a 13.8 kDa protein containing 125 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.

Physical form

Sterile filtered and then lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can then be diluted into other aqueous buffers.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
61007
40407

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Juan Sierra-Marquez et al.
Frontiers in cellular neuroscience, 16, 920075-920075 (2023-05-01)
ClC-3 Cl-/H+ exchangers are expressed in multiple endosomal compartments and likely modify intra-endosomal pH and [Cl-] via the stoichiometrically coupled exchange of two Cl- ions and one H+. We studied pain perception in Clcn3-/- mice and found that ClC-3 not

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