SRP5029
FAK, active, GST tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
FADK, FAK1, FRNK, PTK2, pp125FAK
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352200
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
~140 kDa
recombinant
expressed in baculovirus infected Sf9 cells
product line
PRECISIO® Kinase
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
24-32 nmol/min·mg
mol wt
~140 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... PTK2(5747)
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling
Jimok Yoon
Developmental Cell (2017)
Focal adhesion kinase is involved in rabies virus infection through its interaction with viral phosphoprotein P.
Fouquet B
Journal of Virology (2015)
FAK signaling in anaplastic astrocytoma and glioblastoma tumors.
Natarajan M
Cancer (2003)
Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes.
Gorii GM
Proceedings of the National Academy of Sciences of the USA (2014)
The focal adhesion kinase--a regulator of cell migration and invasion.
Hauck CR
IUBMB Life (2002)
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