SRP5152
14-3-3 α/β, untagged human
recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
14-3-3 α/β, GW128, HS1, KCIP-1, YWHAB
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
recombinant
expressed in E. coli
Assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~29 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... YWHAB(7529)
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
Shumway SD
The Journal of Biological Chemistry, 278(4), 2089-2092 (2003)
14-3-3 family members act coordinately to regulate mitotic progression.
Dalal SN
Cell Cycle, 3(5), 672-677 (2004)
The pro-inflammatory cytokine 14-3-3e is a ligand of CD13 in cartilage.
Nefla M
Journal of Cell Science, 128(17), 3250-3262 (2015)
[Genome-wide association study of allergic diseases in Russians of Western Siberia].
Freidin MB
Molekuliarnaia Biologiia, 45(3), 464-472 (2011)
14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo.
Roy S
Molecular and Cellular Biology, 18(7), 3947-3955 (1998)
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