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Merck
CN

SRP5152

14-3-3 α/β, untagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

14-3-3 α/β, GW128, HS1, KCIP-1, YWHAB

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in E. coli
Mol wt:
~29 kDa
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recombinant

expressed in E. coli

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~29 kDa

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... YWHAB(7529)

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
Shumway SD
The Journal of Biological Chemistry, 278(4), 2089-2092 (2003)
[Genome-wide association study of allergic diseases in Russians of Western Siberia].
Freidin MB
Molekuliarnaia Biologiia, 45(3), 464-472 (2011)
14-3-3 family members act coordinately to regulate mitotic progression.
Dalal SN
Cell Cycle, 3(5), 672-677 (2004)
The pro-inflammatory cytokine 14-3-3e is a ligand of CD13 in cartilage.
Nefla M
Journal of Cell Science, 128(17), 3250-3262 (2015)
14-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis.
Kawamoto Y
Acta Neuropathologica, 108(6), 531-537 (2004)

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