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Merck
CN

SRP6177

CETP human

recombinant, expressed in insect cells, ≥90% (SDS-PAGE)

Synonym(s):

BPIFF, Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I

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About This Item

CAS Number:
NACRES:
NA.32
UNSPSC Code:
12352200
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biological source

human

recombinant

expressed in insect cells

assay

≥90% (SDS-PAGE)

form

lyophilized powder

mol wt

55 kDa

packaging

pkg of 20 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<1 EU/μg (LAL test)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CETP(1071)

General description

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Inhibition of CETP has been proposed as a strategy to raise HDL cholesterol levels, a potential an approach to retarding atherogenesis and a strategy to reduce cardiovascular risk.

Physical form

Lyophilized from a Buffer containing 10 mM Tris and 150 mM NaCl.

Preparation Note

Reconstitute in sterile water at 2 mg/mL.
Centrifuge the vial prior to opening.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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