biological source
human
recombinant
expressed in insect cells
assay
≥90% (SDS-PAGE)
form
lyophilized powder
mol wt
55 kDa
packaging
pkg of 20 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<1 EU/μg (LAL test)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CETP(1071)
General description
Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Inhibition of CETP has been proposed as a strategy to raise HDL cholesterol levels, a potential an approach to retarding atherogenesis and a strategy to reduce cardiovascular risk.
Physical form
Lyophilized from a Buffer containing 10 mM Tris and 150 mM NaCl.
Preparation Note
Reconstitute in sterile water at 2 mg/mL.
Centrifuge the vial prior to opening.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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