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Merck
CN

SRP6210

Sigma-Aldrich

CTGFL/WISP-2 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym(s):

CCN5, CT-58, Cutaneous T-cell Attracting Chemokine

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About This Item

UNSPSC Code:
12352202
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biological source

human

recombinant

expressed in E. coli

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

mol wt

24.3 kDa

packaging

pkg of 10 and 20 μg

impurities

<1 EU/μg endotoxin (LAL test)

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CTGFL(8839)

General description

CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.

Physical form

Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not raise to neutral pH. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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