SRP6363
KLRB1 human
recombinant, expressed in E. coli, ≥85% (SDS-PAGE)
Synonym(s):
CD161, CLEC5B, Killer cell lectin-like receptor subfamily B member 1, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352200
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥85% (SDS-PAGE)
Form:
liquid
Mol wt:
21 kDa (183 aa, 67-225 aa + His Tag)
biological source
human
recombinant
expressed in E. coli
assay
≥85% (SDS-PAGE)
form
liquid
mol wt
21 kDa (183 aa, 67-225 aa + His Tag)
packaging
pkg of 100 μg
concentration
1 mg/mL
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KLRB1(3820)
General description
Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Physical form
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Alba Llibre et al.
Journal of immunology (Baltimore, Md. : 1950), 196(5), 2085-2094 (2016-02-03)
Germinal centers (GCs) are microanatomical structures critical for the development of high-affinity Abs and B cell memory. They are organized into two zones, light and dark, with coordinated roles, controlled by local signaling. The innate lectin-like transcript 1 (LLT1) is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SRP6363-100UG | 04061837252303 |