SRP6509
Chymotrypsin from human pancreas
≥95% (SDS-PAGE)
Synonym(s):
CLCR, CTRC, CTRC_HUMAN, Caldecrin, Chymotrypsin C, Chymotrypsin-C, ELA 4, Elastase 4, Elastase IV, Serum calcium decreasing factor
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
UNSPSC Code:
12352204
EC Number:
232-671-2
NACRES:
NA.78
Form:
lyophilized
Assay:
≥95% (SDS-PAGE)
Biological source:
human
Mol wt:
25 kDa
biological source
human
assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
25 kDa
packaging
pkg of 100 μg
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CTRC(11330)
General description
Chymotrypsin from human pancreas is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. It is secreted by the pancreas as inactive chymotrypsinogen C. Molecular weight of this enzyme is found to be 25kDa. The pI is 8.75.
Biochem/physiol Actions
Chymotrypsin from human pancreas selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan and leucine. Loss-of-function mutations in this gene have been associated with increased risk of chronic pancreatitis. It has high activity toward leucyl peptide bonds. The enzyme acts as a co-activator of procarboxypeptidases A1 and A2.
Physical form
Lyophilized as a salt-free solid.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
Regulatory Information
高风险级别生物产品--人源产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.
Szabo A
The Journal of Biological Chemistry, 290(28), 17282-17292 (2015)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service