SRP6530
NMNAT1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym(s):
EC 2.7.7.1, NMN Adenylyltransferase 1, NaMN Adenylyltransferase 1, Nicotinamide Mononucleotide Adenylyl-transferase 1
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
human
recombinant
expressed in E. coli
Assay
≥95% (SDS-PAGE)
form
liquid
mol wt
monomer ~333 kDa (Human full-length NMNAT1 aa 1-279 is fused at the N-terminus to a His-tag.)
packaging
pkg of 10 and 50 μg
concentration
1 mg/mL
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... NMNAT1(64802)
General description
This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed.
Physical form
1 mg/mL in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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