SRP6560
Wnt-2 human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
INT1L1, IRP, Int-1-like protein 1, Int-1-related protein
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Product Name
Wnt-2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
lyophilized
mol wt
39.9 kDa
packaging
pkg of 1 mg
pkg of 10 μg
pkg of 50 μg
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... WNT2(7472)
Biochem/physiol Actions
Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers.
Physical form
Lyophilized without additives.
Preparation Note
Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Wnt2 complements Wnt/?-catenin signaling in colorectal cancer
Youn-Sang Jung
Oncotarget, 6(35), 37257-37268 (2015)
Overexpression of Wnt-2 in colorectal cancers.
Park JK
Neoplasma, 56(2), 119-123 (2009)
Wnt signal transduction pathways
Yuko Komiya
Organogenesis, 4(2), 68-75 (2008)
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