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Merck
CN

SRP6563

Sigma-Aldrich

BrdT (257-382) human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

Synonym(s):

CT9, Cancer/testis antigen 9, RING3-like protein

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
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biological source

human

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE)

form

liquid

mol wt

14.9 kDa (126 aa, 257-382 aa + NT His Tag)

packaging

pkg of 1 mg
pkg of 100 μg
pkg of 20 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRDT(676)

General description

BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. Therecombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.

Physical form

rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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