SRP8031
FNDC5
recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
Synonym(s):
Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352200
Form:
lyophilized
Assay:
>95% (SDS-PAGE)
Recombinant:
expressed in E. coli
Mol wt:
~16 kDa
recombinant
expressed in E. coli
conjugate
untagged
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~16 kDa
packaging
pkg of 10 μg
impurities
<0.01 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FNDC5(252995)
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General description
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 100 μL deionized water.
Other Notes
FNDC5 (extracellular domain, human (aa 32-152) / mouse (aa 29-149)) is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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