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About This Item
Empirical Formula (Hill Notation):
C20H31NO · HCl
CAS Number:
Molecular Weight:
337.93
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
form
solid
color
white
solubility
methanol: soluble 50 mg/ml, clear to hazy, colorless
H2O: soluble
SMILES string
Cl[H].OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3
InChI
1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H
InChI key
QDWJJTJNXAKQKD-UHFFFAOYSA-N
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Application
DL-Trihexyphenidyl hydrochloride has been used to develop a capillary zone electrophoretic method with end-column electrochemiluminescence (ECL)-based detection technique.
Biochem/physiol Actions
DL-trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is known to function as an antimuscarinic agent and a centrally acting anticholinergic. It can be used for controlling the symptoms of all Parkinsonism types, such as the idiopathic, and postencephalitic arteriosclerotic forms. Benzhexol hydrochloride exerts inhibitory functions on the parasympathetic nervous system.
Muscarinic acetylcholine receptor antagonist
Preparation Note
DL-Trihexyphenidyl hydrochloride is soluble in water. It dissolves in methanol at 50 mg/ml to yield a clear to hazy, colorless solution.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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