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T164

Testosterone 17β-cypionate

Name: Testosterone 17β-cypionate
Brand: SIGMA

Synonym(s):

17β-Hydroxy-4-androsten-3-one 17-cyclopentylpropionate, 4-Androsten-17β-ol-3-one 17-cypionate, Depotestosterone, Depovirin, Testosterone 17β-cyclopentanepropionate

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₄₀O₃

CAS Number:

58-20-8

Molecular Weight:

412.60

UNSPSC Code:

41116107

PubChem Substance ID:

329826683

EC Number:

200-368-4

MDL number:

MFCD00053944

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drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

water: <0.5 mg/mL

format

neat

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CCC5CCCC5

InChI

1S/C27H40O3/c1-26-15-13-20(28)17-19(26)8-9-21-22-10-11-24(27(22,2)16-14-23(21)26)30-25(29)12-7-18-5-3-4-6-18/h17-18,21-24H,3-16H2,1-2H3/t21-,22-,23-,24-,26-,27-/m0/s1

InChI key

HPFVBGJFAYZEBE-ZLQWOROUSA-N

Gene Information

human ... AR(367)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H351,H361,H410

pcodes

P201 - P273 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Change in prostate specific antigen following androgen stimulation is an independent predictor of prostate cancer diagnosis.

Robert S Svatek et al.

The Journal of urology, 179(6), 2192-2195 (2008-04-22)

We tested the hypothesis that a single exogenous androgen injection in men with low prostate specific antigen would provoke a differential prostate specific antigen response that would correlate with the presence and volume of cancer at biopsy. Following institutional review

Effects of testosterone replacement in middle-aged men with dysthymia: a randomized, placebo-controlled clinical trial.

Stuart N Seidman et al.

Journal of clinical psychopharmacology, 29(3), 216-221 (2009-05-15)

Mid-life onset male dysthymic disorder (DD) seems to be a distinct clinical condition with limited therapeutic options. Testosterone replacement is mood-enhancing and has been proposed as an antidepressant therapy, though this strategy has received limited systematic study. We therefore conducted

Repeated anabolic/androgenic steroid exposure during adolescence alters phosphate-activated glutaminase and glutamate receptor 1 (GluR1) subunit immunoreactivity in Hamster brain: correlation with offensive aggression.

Shannon G Fischer et al.

Behavioural brain research, 180(1), 77-85 (2007-04-10)

Male Syrian hamsters (Mesocricetus auratus) treated with moderately high doses (5.0mg/kg/day) of anabolic/androgenic steroids (AAS) during adolescence (P27-P56) display highly escalated offensive aggression. The current study examined whether adolescent AAS-exposure influenced the immunohistochemical localization of phosphate-activated glutaminase (PAG), the rate-limiting

Influence of anabolic combinations of an androgen plus an estrogen on biochemical pathways in bovine uterine endometrium and ovary.

C Becker et al.

The Journal of steroid biochemistry and molecular biology, 125(3-5), 192-201 (2011-01-29)

The application of anabolic steroids in food producing animals is forbidden in the EU since 1988, but the abuse of such drugs is a potential problem. The existing test systems are based on known compounds and can be eluded by

Anterior hypothalamic dopamine D2 receptors modulate adolescent anabolic/androgenic steroid-induced offensive aggression in the Syrian hamster.

Jared J Schwartzer et al.

Behavioural pharmacology, 21(4), 314-322 (2010-06-18)

In the Syrian hamster, treatment with anabolic/androgenic steroids (AAS) throughout adolescence increases dopamine and D2 receptor expression in the anterior hypothalamus (AH), a brain region implicated in the control of aggression. D2 receptor antagonists have reduced aggression in various species

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