T1700
Anti-phospho-Tau (pSer400) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
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About This Item
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
western blot: 1:1,000 using recombinant human Tau stimulatd with GSK-3β
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... MAPT(4137)
mouse ... Mapt(17762)
rat ... Mapt(29477)
Immunogen
synthetic phosphopeptide derived from a region of human Tau that contains serine 400. The sequence is conserved in many species including mouse, rat, baboon, rhesus monkey, cow, and goat. Mouse, rat, and other species have not been tested.
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), 50% glycerol with 1 mg/mL BSA (IgG, protease free), and 0.05% sodium azide.
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J Z Wang et al.
FEBS letters, 436(1), 28-34 (1998-10-15)
Alzheimer disease is characterized by a specific type of neuronal degeneration in which the microtubule associated protein tau is abnormally hyperphosphorylated causing the disruption of the microtubule network. We have found that the phosphorylation of human tau (tau3L) by A-kinase
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