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Merck
CN

T2777

Anti-3,3′,5-Triiodo-L-Thyronine (T3) antibody produced in rabbit

whole antiserum

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About This Item

UNSPSC Code:
12352203
MDL number:
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biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

radioimmunoassay: 1:6,000

shipped in

dry ice

storage temp.

−20°C

Immunogen

T3-BSA

Application

Anti-3,3′,5-Triiodo-L-Thyronine (T3) antibody produced in rabbit was used in flow cytometry analysis of hormone content of rat white blood cells and mast cells.

Biochem/physiol Actions

3,3′,5-Triiodo-L-Thyronine (T3) is the most biologically active form of thyroid hormone that is a key regulator of metabolism, heart, muscle and digestive functions, brain development and maintenance of bone density. The effects of T3 are mediated by its binding to thyroid hormone receptors expressed on human hepatocytes.

Preparation Note

Dilute with buffer: 0.01 M phosphate, pH 7.4, 0.15 M sodium chloride and 15 mM sodium azide.

Analysis Note

Secondary antibody-polyethylene glycol 125I RIA

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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K H Clifton et al.
Journal of radiation research, 32 Suppl 2, 143-155 (1991-12-01)
We have presented evidence that the functional thyroid follicles (follicular units, FU) which are formed in grafts of monodispersed rat thyroid cells, and hence the thyroid tumors which later develop in such grafts, are clonal in origin. Transplantation assays indicate
Joseph Wang et al.
Electrophoresis, 23(21), 3744-3749 (2002-11-15)
A new chip-based electrochemical immunoassay protocol, based on the use of a ferrocene redox label, is described. Two reaction formats, based on direct (noncompetitive) and competitive modes of operation, were employed for illustrating the use of redox tracers in chip-based
G Csaba et al.
Cell biology international, 31(9), 924-928 (2007-04-06)
Tetrahymena contains vertebrate hormone-like materials. The level of one of these, insulin increased during starvation in a previous experiment. We hypothesized that other hormones are also influenced by starvation. To prove the hypothesis Tetrahymena pyriformis cultures were (1) starved for
M A Campinho et al.
The Journal of experimental biology, 209(Pt 23), 4751-4767 (2006-11-23)
In the sea bream Sparus auratus three stage-specific fast troponin T (fTnT) isoforms have been cloned and correspond to embryonic-, larval- and adult-specific isoforms. Characterisation, using database searches, of the putative genomic organisation of Fugu rubripes and Tetraodon nigroviridis fTnT
Andre Lima Queiroz et al.
Nature communications, 13(1), 4633-4633 (2022-08-09)
Cancer cachexia is a common, debilitating condition with limited therapeutic options. Using an established mouse model of lung cancer, we find that cachexia is characterized by reduced food intake, spontaneous activity, and energy expenditure accompanied by muscle metabolic dysfunction and

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