T2830
Tomatine hydrate
≥95% (HPLC)
Synonym(s):
Lycopersicin, NSC 234440, NSC 9223, Spirosolane, a-Tomatine, alpha-tomatine, b-D-galactopyranoside deriv
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About This Item
Empirical Formula (Hill Notation):
C50H83NO21 · xH2O
CAS Number:
Molecular Weight:
1034.19 (anhydrous basis)
EC Number:
241-429-5
UNSPSC Code:
12352200
assay
≥95% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >20 mg/mL
storage temp.
room temp
Application
Tomatine has been used as a standard for HPLC-based determination of tomatine from red and green tomatoes1. It has also been used to study its teratogenic effect using frog embryos2.
Biochem/physiol Actions
When the pure compounds were isolated, alpha-Tomatine was highly effective in inhibiting all of the cell lines, whereas dehydrotomatine, tomatidenol, and tomatidine had little, if any, effect on cell inhibition. It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.
It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.
Preparation Note
Tomatine hydrate is soluble in DMSO at a concentration that is greater than 20 mg/ml.
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