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About This Item
Empirical Formula (Hill Notation):
C16H14N2O2
CAS Number:
Molecular Weight:
266.29
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥98%
form
powder
solubility
methylene chloride: soluble 10 mg/mL
DMSO: soluble
storage temp.
2-8°C
SMILES string
COc1cc2ncc(nc2cc1OC)-c3ccccc3
InChI
1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
InChI key
QNOXYUNHIGOWNY-UHFFFAOYSA-N
Biochem/physiol Actions
Selective inhibitor of platelet-derived growth factor (PDGF) receptor protein.
Studies have reported that phosphorylation of tyrosine 857 in PDGF β-receptor is the most susceptible to inhibition by tyrphostin AG 12962.
Preparation Note
Tyrphostin AG 1296 is soluble in methylene chloride at 10 mg/ml and is also soluble in DMSO.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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