T4157
Tuftsin Fragment 1-3 acetate salt monohydrate
≥97% (HPLC)
Synonym(s):
Thr-Lys-Pro
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About This Item
Empirical Formula (Hill Notation):
C15H28N4O5 · H2O · xC2H4O2
Molecular Weight:
362.42 (free base basis)
UNSPSC Code:
12352200
MDL number:
assay
≥97% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Macrophage inhibitory peptide.
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C Auriault et al.
FEBS letters, 153(1), 11-15 (1983-03-07)
We have shown that IgG hydrolysed by Schistosoma mansoni schistosomula inhibited various macrophage functions, especially phagocytosis and anti-schistosome cytotoxicity. Here we show that a tripeptide, Thr289-Lys-Pro291, of the second constant domain of human immunoglobulin G (peptide 286-292) reproduced the inhibitory
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