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T4157

Tuftsin Fragment 1-3 acetate salt monohydrate

≥97% (HPLC)

Synonym(s):

Thr-Lys-Pro

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About This Item

Empirical Formula (Hill Notation):
C15H28N4O5 · H2O · xC2H4O2
Molecular Weight:
362.42 (free base basis)
UNSPSC Code:
12352200
MDL number:
MFCD00133888
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assay

≥97% (HPLC)

storage temp.

−20°C

Biochem/physiol Actions

Macrophage inhibitory peptide.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
064K1284
089F58402
039H1138
024K0679
121K1389

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C Auriault et al.
FEBS letters, 153(1), 11-15 (1983-03-07)
We have shown that IgG hydrolysed by Schistosoma mansoni schistosomula inhibited various macrophage functions, especially phagocytosis and anti-schistosome cytotoxicity. Here we show that a tripeptide, Thr289-Lys-Pro291, of the second constant domain of human immunoglobulin G (peptide 286-292) reproduced the inhibitory