T4509
4-Thiouridine
≥98%, synthetic (organic), powder
Synonym(s):
4sU, RNA synthesis inhibitor, Thiouridine
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About This Item
Empirical Formula (Hill Notation):
C9H12N2O5S
CAS Number:
Molecular Weight:
260.27
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
237-735-3
MDL number:
Assay:
≥98%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 20 mg/mL, clear
Storage temp.:
−20°C
Product Name
4-Thiouridine, ≥98%
biological source
synthetic (organic)
Quality Segment
assay
≥98%
form
powder
solubility
water: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=S)NC2=O
InChI
1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1
InChI key
ZLOIGESWDJYCTF-XVFCMESISA-N
General description
4-Thiouridine is a photoreactive uridine analog.
Application
4-Thiouridine has been used in labeling and isolation of nascent RNAs.
Biochem/physiol Actions
4-Thiouridine plays a role in assessing nascent RNA synthesis. It also enhances site-specific crosslinking. 4-Thiouridine also acts as a photoaffinity probe due to its stability even while lacking specific photoactivation. It can also be incorporated into RNAs.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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