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T4905

Tri-O-thymotide

Name: Tri-O-thymotide
Brand: SIGMA

Synonym(s):

Cyclic trilactone of o-thymotic acid

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About This Item

Empirical Formula (Hill Notation):

C₃₃H₃₆O₆

CAS Number:

4399-52-4

Molecular Weight:

528.64

UNSPSC Code:

12352200

PubChem Substance ID:

329826802

MDL number:

MFCD00075324

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Properties

mp

219-221 °C (lit.)

SMILES string

CC(C)c1ccc(C)c2C(=O)Oc3c(ccc(C)c3C(=O)Oc4c(ccc(C)c4C(=O)Oc12)C(C)C)C(C)C

InChI

1S/C33H36O6/c1-16(2)22-13-10-19(7)25-28(22)37-32(35)26-20(8)11-14-23(17(3)4)29(26)39-33(36)27-21(9)12-15-24(18(5)6)30(27)38-31(25)34/h10-18H,1-9H3

InChI key

ZIKHLMVJGCYVAC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Host substance for formation of clathrates (inclusion complexes).

Other Notes

Cyclic trilactone of thymotic acid (3-isopropylsalicylic acid).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Eaton, D.F.

Journal of the American Chemical Society, 109, 1886-1886 (1987)

Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.

Katherine I Zhou et al.

Molecular cell, 76(1), 70-81 (2019-08-26)

N6-methyladenosine (m6A) modification occurs co-transcriptionally and impacts pre-mRNA processing; however, the mechanism of co-transcriptional m6A-dependent alternative splicing regulation is still poorly understood. Heterogeneous nuclear ribonucleoprotein G (hnRNPG) is an m6A reader protein that binds RNA through RRM and Arg-Gly-Gly (RGG)