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Merck
CN

T5193

Tyrphostin AG 698

≥98%

Synonym(s):

N-(2-Phenylethyl)-3,4-dihydroxybenzylidenecyanoacetamide, Tyrphostin B52

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O3
Molecular Weight:
308.33
UNSPSC Code:
12352200
PubChem Substance ID:
24278743
MDL number:
MFCD00209864

Key Documents

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SMILES string

Oc1ccc(cc1O)\C=C(/C#N)C(=O)NCCc2ccccc2

assay

≥98%

potency

IC50 (930 nanomolar for inhibition of EGFR-kinase activity.)

solubility

DMSO or ethanol: soluble

storage temp.

−20°C

Gene Information

human ... EGFR(1956), ERBB2(2064)

Biochem/physiol Actions

EGFR protein tyrosine kinase inhibitor.

Preparation Note

Tyrphostin AG 698 is soluble in DMSO and ethanol.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
061K1645

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