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Merck
CN

T5316

TAPS

BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

Synonym(s):

N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H17NO6S
CAS Number:
Molecular Weight:
243.28
EC Number:
249-954-1
UNSPSC Code:
12161700
PubChem Substance ID:
Beilstein/REAXYS Number:
2452420
MDL number:
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grade

BioPerformance Certified

assay

≥99.5% (titration)

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

useful pH range

7.7-9.1

pKa 

8.4

mp

230-235 °C (dec.)

solubility

water: 0.5 g/mL, clear, colorless

cation traces

heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, protease, none detected

SMILES string

OCC(CO)(CO)NCCCS(O)(=O)=O

InChI

1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)

InChI key

YNLCVAQJIKOXER-UHFFFAOYSA-N



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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

>230.0 °F - closed cup

flash_point_c

> 110 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)



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Z Zeng et al.
Analytical biochemistry, 252(1), 110-114 (1997-11-05)
High-resolution capillary electrophoresis sizing of preformed complexes of bis-intercalating fluorescent dyes with double-stranded DNA has been demonstrated using hydroxyethylcellulose and 3-[tris-(hydroxymethyl) methylamino]-1-propanesulfonic acid-tetrapentylammonium (Taps-NPe+4) buffers (S. M. Clark and R. A. Mathies, Anal. Chem. 69, 1355-1363, 1997). Such capillary electrophoresis
D Liang et al.
Electrophoresis, 21(17), 3600-3608 (2001-03-29)
A new method to introduce the concentration gradient into the capillary has been developed and its application to DNA capillary electrophoresis is presented. The concentration gradient produced by mixing 5% w/v polyacrylamide-co-poly(N-dimethylacrylamide) (PAM-co-PDMA) solution and 1 x Tris/N-tris(hydroxymethyl)methyl-3-amino-propanesulfonic acid/EDTA (TT)
Seung-ick Oh et al.
TheScientificWorldJournal, 2014, 957548-957548 (2014-07-06)
Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here



Global Trade Item Number

SKUGTIN
T5316-500G04061833624821
T5316-100G04061833436028
T5316-1KG04061826759141
T5316-25G04061833613900