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T5379

Tyr-Phe

Name: Tyr-Phe
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₀N₂O₄

CAS Number:

17355-11-2

Molecular Weight:

328.36

NACRES:

NA.26

PubChem Substance ID:

24900270

UNSPSC Code:

12352200

MDL number:

MFCD00037255

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Properties

assay

≥98% (TLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

NC(Cc1ccc(O)cc1)C(=O)NC(Cc2ccccc2)C(O)=O

InChI

1S/C18H20N2O4/c19-15(10-13-6-8-14(21)9-7-13)17(22)20-16(18(23)24)11-12-4-2-1-3-5-12/h1-9,15-16,21H,10-11,19H2,(H,20,22)(H,23,24)

InChI key

CGWAPUBOXJWXMS-UHFFFAOYSA-N

Description

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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A new cytochrome C reducing dipeptide.

C Simpkins

Journal of the National Medical Association, 82(2), 113-116 (1990-02-01)

Using absorption spectroscopy, it has been found that tyrosylphenylalanine specifically reduces cytochrome C. This effect is pH and concentration dependent with the EC +/- SE = 4.42 x 10(-3) M. At 10(-2) 2 M, tyrosylphenylalanine caused reduction which was 50%

The effect of neighboring methionine residue on tyrosine nitration and oxidation in peptides treated with MPO, H2O2, and NO2(-) or peroxynitrite and bicarbonate: role of intramolecular electron transfer mechanism?

Hao Zhang et al.

Archives of biochemistry and biophysics, 484(2), 134-145 (2008-12-06)

Recent reports suggest that intramolecular electron transfer reactions can profoundly affect the site and specificity of tyrosyl nitration and oxidation in peptides and proteins. Here we investigated the effects of methionine on tyrosyl nitration and oxidation induced by myeloperoxidase (MPO)

Interaction between cytochrome C and di- and tripeptides.

C Simpkins et al.

Life sciences, 48(6), 523-530 (1991-01-01)

By observing changes in the absorbance spectrum between 340 and 650 nm, we found that tyrosyltyrosylphenylalanine (TTP) interacts with cytochrome C (CC). TTP caused the characteristic changes of CC reduction, namely, an increased optical density at 524 and 550 nm

Global Trade Item Number

SKU	GTIN
T5379-250MG	04061832892276