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Merck
CN

T5513

N,N,N′,N′-Tetramethylbenzidine

≥95% (HPLC)

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About This Item

Linear Formula:
[-C6H4-4-N(CH3)2]2
CAS Number:
Molecular Weight:
240.34
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
206-676-5
MDL number:
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InChI key

YRNWIFYIFSBPAU-UHFFFAOYSA-N

InChI

1S/C16H20N2/c1-17(2)15-9-5-13(6-10-15)14-7-11-16(12-8-14)18(3)4/h5-12H,1-4H3

SMILES string

CN(C)c1ccc(cc1)-c2ccc(cc2)N(C)C

assay

≥95% (HPLC)

form

powder

mp

193-195 °C (lit.)

Quality Level

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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C Stürmer et al.
Neuroscience letters, 23(1), 1-5 (1981-04-09)
Tetramethylbenzidine (TMB) histochemistry for retrogradely transported horseradish peroxidase (HRP) has been successfully applied in electron microscopical preparations in the guinea pig visual cortex. In ultrathin sections, the TMB--HRP reaction product appears as an accumulation of typical electron-dense crystals. These crystals
T M Bricker et al.
Biochimica et biophysica acta, 1409(1), 50-57 (1998-11-07)
Site-directed mutagenesis was used to produce a Synechocystis mutant containing a histidine tag at the C terminus of the CP 47 protein of Photosystem II. This mutant cell line, designated HT-3, exhibited slightly above normal rates of oxygen evolution and
L G McGirr et al.
Chemico-biological interactions, 61(1), 61-74 (1987-01-01)
The mechanism of peroxidative N-dealkylation of alkylamines proceeds via one-electron oxidation to the iminium cation which reacts with water to give the N-hydroxymethyl derivative which decomposes to formaldehyde and the N-demethylated product. This reaction is normally inhibited by glutathione by
P C Andrews et al.
Archives of biochemistry and biophysics, 228(2), 439-442 (1984-02-01)
It has been demonstrated previously (P.C. Andrews and N.I. Krinsky (1981) J. Biol. Chem. 256, 4211-4218) that human leukocyte myeloperoxidase, an alpha 2 beta 2 enzyme, can be cleaved by mild reduction and alkylation to an alpha 1 beta 1
A P Kulkarni et al.
Biochemical and biophysical research communications, 155(2), 1075-1081 (1988-09-15)
Since H2O2 is one of the major biologically available peroxides, its ability to support hydroperoxidase activity of highly purified soybean lipoxygenase was examined by monitoring co-oxidation of selected xenobiotics. All of the eight chemicals tested were found to be oxidized

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