T5824
TAN-67 dihydrobromide
≥98% (HPLC), solid
Synonym(s):
(3-Hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide, SB-205607 dihydrobromide
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About This Item
Empirical Formula (Hill Notation):
C23H24N2O · 2HBr
CAS Number:
Molecular Weight:
506.27
UNSPSC Code:
12352200
MDL number:
description
Store tightly sealed under nitrogen
assay
≥98% (HPLC)
form
solid
color
off-white
solubility
H2O: soluble >20 mg/mL
storage temp.
2-8°C
SMILES string
Br[H].Br[H].[H][C@@]12CN(C)CC[C@]1(Cc3nc4ccccc4cc3C2)c5cccc(O)c5
Biochem/physiol Actions
Potent, selective non-peptide δ opioid receptor agonist.
Legal Information
Sold for research purposes under agreement from GlaxoSmithKline
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Hemal H Patel et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 16(11), 1468-1470 (2002-09-03)
Opioids and volatile anesthetics produce marked cardioprotective effects against myocardial infarction via the activation of ATP-sensitive potassium (K(ATP)) channels, however, the effect of combined treatment with both drugs is unknown. We examined the hypothesis that opioids and volatile anesthetics potentiate
R M Fryer et al.
The Journal of pharmacology and experimental therapeutics, 299(2), 477-482 (2001-10-17)
We investigated the possibility that opioids activate a tyrosine kinase (TK) that mediates cardioprotection in an in vivo rat model of myocardial infarction. All animals underwent 30 min of regional ischemia and 2 h of reperfusion. Infarct size was expressed