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T5943

Tyrphostin AG 1007

≥98%, solid

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About This Item

Empirical Formula (Hill Notation):
C17H14N2O2S
CAS Number:
148741-32-6
Molecular Weight:
310.37
NACRES:
NA.77
MDL number:
MFCD01868802
UNSPSC Code:
51112000
Assay:
≥98%
Form:
solid
Quality level:
200
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Quality Level

200

assay

≥98%

form

solid

color

yellow to green

solubility

DMSO: soluble, acetone: soluble

storage temp.

−20°C

Biochem/physiol Actions

Tyrphostin AG 1007 is known to function as a receptor tyrosine kinase inhibitor. It has been reported that replacement of oxygen in the carbonyl group of AG-1007 significantly increased the inhibition of tyrosine autophosphorylation of IGF-1R1.

Preparation Note

Tyrphostin AG 1007 is soluble in DMSO and acetone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
053K1210
053K1261

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G Blum et al.
Biochemistry, 39(51), 15705-15712 (2000-12-22)
IGF-1 and its receptor play a pivotal role in many cancers, and therefore, IGF-1R is an attractive target for the design of inhibitors. In this communication, we report on a number of lead compounds for inhibitors of the isolated IGF-1R

Global Trade Item Number

SKUGTIN
T5943-1MG04061826133200