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Merck
CN

T6023

(±)-Thiopental sodium salt sodium carbonate mixture

Synonym(s):

5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, Pentothal

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About This Item

Empirical Formula (Hill Notation):
C11H17N2NaO2S
CAS Number:
71-73-8
Molecular Weight:
264.32
UNSPSC Code:
12352200
EC Number:
200-763-1
PubChem Substance ID:
24900339

Key Documents

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SMILES string

[Na].[Na+].[Na+].[O-]C([O-])=O.CCCC(C)C1(CC)C(=O)NC(=S)NC1=O

composition

Thiopental sodium, ~91% (remainder is sodium carbonate)

drug control

USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

H2O: >10 mg/mL, alcohol: soluble

Biochem/physiol Actions

Intravenous anesthetic

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
063H0825
058F0347
100K1687

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Y F Huang et al.
Journal of pharmaceutical sciences, 87(7), 854-858 (1998-07-02)
Previous reports have suggested that tachycardia alone can increase the rate of myocardial uptake of some drugs. As part of a systematic study of the determinants of the myocardial uptake and effects of drugs in critical illness, the effect of
H Qu et al.
Biochemical pharmacology, 58(6), 1075-1080 (1999-10-06)
The effect of thiopental on glutamate metabolism was studied by 13C magnetic resonance spectroscopy. Cerebral cortical astrocytes were incubated with 0.5 mM [U-13C]glutamate for 2 hr in the presence of 0.5 or 1 mM thiopental. Labeled glutamate, glutamine, aspartate, and

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