T9306
Tag-72 antigen from human fluids
buffered aqueous solution
Synonym(s):
Cancer-associated Ca-72-4
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About This Item
UNSPSC Code:
12352202
MDL number:
biological source
human fluids
form
buffered aqueous solution
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Expression of TAG-72 was shown to be induced by interferon α treatment in patients with colorectal cancer.
Physical form
Solution in 0.15 M phosphate buffered saline, pH 7.4, containing 0.1% sodium azide.
Analysis Note
Partially purified
Other Notes
One unit is an arbitrary amount related to a reference antigen preparation using CIS-RIA method.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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V G Johnson et al.
Cancer research, 46(2), 850-857 (1986-02-01)
Monoclonal antibody B72.3 binds a high-molecular-weight tumor-associated glycoprotein identified as TAG-72. This study reports the partial purification and characterization of TAG-72 from a xenograft of a human carcinoma cell line, LS-174T, which expresses high levels of this antigen. The tumor
D M Mahvi et al.
Cancer immunology, immunotherapy : CII, 40(5), 311-314 (1995-05-01)
Interferons up-regulate the expression of human tumor-associated antigens in animal models and in vitro. The use of interferons may enhance the immunodetection and immunotherapy of tumors by monoclonal antibodies that detect tumor antigens. For this strategy to be effective, however
A E Evans et al.
Cancer, 38(2), 661-666 (1976-08-01)
A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system
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