biological source
mouse
recombinant
expressed in E. coli
Assay
>97% (SDS-PAGE)
form
lyophilized powder
potency
0.66 μg/mL
mol wt
16-17 kDa by SDS-PAGE (doublet)
predicted mol wt ~14 kDa
packaging
pkg of 25 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Ccl25(20300)
Application
The interaction of TECK and its receptor CCR9 plays a pivotal role in recruiting the developing thymocytes to their distinct compartment of the thymus.
Biochem/physiol Actions
TECK, a CC chemokine, is chemotactic for activated macrophages, dendritic cells, and thymocytes.
Thymus-expressed chemokine (TECK) belongs to CC chemokine and is expressed mainly in thymus and small intestine. It can facilitate chemotaxis of human G protein-coupled receptor GPR-9-6/L1.2 transfectants. Further, TECK potentially assists in T Cell Development.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing at least 50 μg bovine serum albumin per 1 μg of cytokine.
Analysis Note
The biological activity is measured by its ability to chemoattract hCCR9 transfected BaF/3 cells.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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