T9758
Thymidine 5′-monophosphate
98-100%
Synonym(s):
TMP, Thymidylic acid, dTMP
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About This Item
Empirical Formula (Hill Notation):
C10H15N2O8P
CAS Number:
Molecular Weight:
322.21
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
assay
98-100%
storage temp.
−20°C
SMILES string
CC1=CN(C2CC(O)C(COP(O)(O)=O)O2)C(=O)NC1=O
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Andreas Stahl Madsen et al.
The Journal of organic chemistry, 77(23), 10718-10728 (2012-11-14)
Thymine intermediate 17 has been synthesized on a multigram scale (50 g, 70 mmol) from starting sugar 1 in 15 steps in an overall yield of 73%, with only 5 purification steps. The key thymine intermediate 18 was obtained from
Brant E Billinghurst et al.
The journal of physical chemistry. B, 116(35), 10496-10503 (2012-06-16)
Thymine is one of the pyrimidine nucleobases found in DNA. Upon absorption of UV light, thymine forms a number of photoproducts, including the cyclobutyl photodimer, the pyrimidine pyrimidinone [6-4] photoproduct and the photohydrate. Here, we use UV resonance Raman spectroscopy
Sanjay Adhikari et al.
Analytical biochemistry, 416(1), 112-116 (2011-05-31)
Tyrosyl DNA phosphodiesterase 2 (TDP2), a newly discovered enzyme that cleaves 5'-phosphotyrosyl bonds, is a potential target for chemotherapy. TDP2 possesses both 3'- and 5'-tyrosyl-DNA phosphodiesterase activity, which is generally measured in a gel-based assay using 3'- and 5'-phosphotyrosyl linkage
Shiqiong Yang et al.
Chemistry & biodiversity, 9(10), 2186-2194 (2012-10-20)
A series of d4T di- or triphosphate derivatives have been synthesized and evaluated as effective substrates for HIV-1 RT, and also tested for their in vitro anti-HIV activity. The steady-state kinetic study of compounds 1-4 in an enzymatic incorporation assay
Linlin Yang et al.
Journal of the American Chemical Society, 133(27), 10434-10447 (2011-06-16)
5-Thyminyl-5,6-dihydrothymine (commonly called spore photoproduct or SP) is the exclusive DNA photodamage product in bacterial endospores. It is generated in the bacterial sporulation phase and repaired by a radical SAM enzyme, spore photoproduct lyase (SPL), at the early germination phase.
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