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Merck
CN

U8132

[pGlu110]-Prepro-Urotensin II Fragment 110-123 rat

>98% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):
C77H102N18O20S2
Molecular Weight:
1663.87
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
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assay

>98% (HPLC)

form

solid

UniProt accession no.

storage temp.

−20°C

Gene Information

rat ... Uts2(29180)

Application

Rat [pGlu110]-Prepro-Urotensin II Fragment 110-123 may be used for cell biology, cell signaling and neuroscience studies.

Biochem/physiol Actions

Potent vasoconstrictor.
Rat Urotensin II is a neuroendocrine peptide that belongs to CRF family and possesses regionally-selective vasodilator impact on conscious rats. It also induces potent vasoconstriction in humans in vivo.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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S M Gardiner et al.
British journal of pharmacology, 132(8), 1625-1629 (2001-04-20)
The regional haemodynamic effects of rat or human urotensin II (U-II) 3, 30, 300 and 3000 pmol kg(-1), i.v.) were assessed in separate groups of conscious, unrestrained, male, Sprague-Dawley rats (n=8 in each). Rat and human U-II had similar effects.
Felix Böhm et al.
British journal of pharmacology, 135(1), 25-27 (2002-01-12)
The peptide urotensin II (U II) evokes potent vasoconstriction in non-human primates. In human blood vessels studied in vitro variable effects of U II are reported; vasoconstriction, vasodilatation or no response. It is therefore of importance to determine the vascular



Global Trade Item Number

SKUGTIN
U8132-.5MG04061832784076